PositiveSingles.com - the best, most trusted and largest anonymous STD dating site!

Herpes Survival Kit - a specially designed pack containing everything you need to combat herpes and cold sore outbreaks (at a minimum cost to your wallet).

only search Racoon.com

"The Good News about the Bad News - 
Herpes: Everything You Need to Know
"  
Terri Warren's new book - which we do endorse.

First time visitor? Please Learn about Registering and read our policy page.
{Home}{Awareness}{Research}{Treatment}{HHP FAQ}{Bookstore}{Bio/Info Page}

The Original Herpes Home Page Discussion Forums

Subject: "negative HSV blood test?"     Previous Topic | Next Topic
Printer-friendly copy     Email this topic to a friend    
Conferences Technical Topic #2863
Reading Topic #2863
mschultz1115
Member since Dec-9-08
1 posts
Dec-09-08, 09:34 AM (CST)
Click to EMail mschultz1115 Click to send private message to mschultz1115 Click to add this user to your buddy list  
"negative HSV blood test?"
 
   I'm a 27 year old female. About six years ago, I slept with someone I didn't know very well and developed sores on my genitals as well as a low grade fever and painful enlarged lymph nodes in my groin. I went to the doctor and they swabbed the sores and sent them for culture. A few days later they called to tell me the test was positive for herpes. They never mentioned getting a blood test. The next person I slept with contracted the disease from me, also had a positive culture but never mentioned anything about getting a blood test. Since then, I have never experience another outbreak, atleast not one that I could tell. I have had significant emotional distress over this situation, it traumatized me. I am so terrified to give the virus to someone else again that I completely avoid sex. I have read a lot online over past few years about different test, treatments etc... I decided to go to my new ob/gyn's office and ask for an HSV blood test to figure out which virus I have, 1 or 2. The test was performed and came back negative. I was extremely surprised. I never got a chance to discuss the results with that doctor. Is it common, or even possible to have false negative blood test result? From everything I've read the blood test results are fairly black and white. Also, how is it that I have not had a single recognizable outbreak in six years. I am very conscious of symptoms since the diagnosis and am constantly inspecting my genitals looking for symptoms and never see anything. That's why I completely avoid sex because I'm afraid I just can't tell when I'm having an outbreak. Having just recently changed insurance companies, I have a new doctor whom I told all of the above. He told me that maybe the initial diagnosis was wrong, maybe I don't even have HSV. Bullshit right? Could this even be possible? Should I get another blood test? Thanks for reading.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top

  Subject     Author     Message Date     ID  
  RE: negative HSV blood test? Lenoreadmin Dec-09-08 1
  RE: negative HSV blood test? windyadmin Dec-09-08 2
     RE: negative HSV blood test? zuzzy Dec-10-08 3
         RE: negative HSV blood test? windyadmin Dec-10-08 4
             RE: negative HSV blood test? zuzzy Dec-11-08 5
                 RE: negative HSV blood test? windyadmin Dec-11-08 6
                     RE: negative HSV blood test? auntiejessiadmin Dec-11-08 7
                         RE: negative HSV blood test? graceadmin Dec-12-08 8
                             RE: negative HSV blood test? Angelika Dec-12-08 9
                                 RE: negative HSV blood test? auntiejessiadmin Dec-12-08 10

Conferences | Topics | Previous Topic | Next Topic
Lenoreadmin
Member since Oct-22-04
4277 posts
Dec-09-08, 09:55 AM (CST)
Click to EMail Lenore Click to add this user to your buddy list  
1. "RE: negative HSV blood test?"
In response to message #0
 
   A positive culture means that you have herpes. It's a swab of the actual virus that grows in the culture medium. The only way this could be a mistake is if someone mislabeled the specimen or if someone gave you incorrect information over the phone. Both of those things are possible, but it seems less likely that there would be a second mistake with your next partner also testing positive unless they already had the virus and it wasn't something that they got from you.

There is a small percentage of people (I'm not good with statistics) that will not test positive on a blood test, but I don't think this is very common. It would help if you could post your blood test results and what type of test that you had. Someone can give you a suggestion regarding further testing since there are a few different types of tests.

I'm glad you're pursuing this. It's sad when I hear of someone limiting their life because of this stupid virus. Herpes affects so many people that it really shouldn't be as big of a deal as it is.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
windyadmin
Charter Member
8251 posts
Dec-09-08, 11:14 AM (CST)
Click to EMail windy Click to send private message to windy Click to view user profileClick to add this user to your buddy list  
2. "RE: negative HSV blood test?"
In response to message #0
 
False negative blood tests for hsv2 are rare, assuming the test wasn't done too soon (i.e. earlier than 12-16 weeks after the first outbreak.) False negatives for hsv1 are more common. It can miss around 20% of them, depending on the source you look at. The fact that you've not had any outbreaks in six years suggests that you might have genital hsv1, although there are a lot of people with hsv2 who don't get outbreaks.

If you do get another blood test, I'd recommend that you get a Western Blot and make sure the lab has your history (positive culture, long time with no outbreaks and negative blood test.) They can do some tricks to get a more reliable answer.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
zuzzy
Member since Dec-10-08
3 posts
Dec-10-08, 03:28 PM (CST)
Click to EMail zuzzy Click to send private message to zuzzy Click to view user profileClick to add this user to your buddy list  
3. "RE: negative HSV blood test?"
In response to message #2
 
   I'd really like to know the statistics on negative blood tests.

I cultured positive for HSV II in March, but 6 months after the intial OB, I still had a negative IGG bloodtest. (Result "< .91") I used labcorp, not sure on the brand name of the test.

Initally I was worried that not testing positive on the blood test would somehow mean the outbreaks would be more problematic. Posted on medhelp and they said severity of symptoms are not related to whether or not you blood test positve. However, I would say I have more than the average number of outbreaks (more than 10 per year).

The interesting thing was that I did test positive for HSV Type 1. I had this done twice (with the same results) to confirm no lab error.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
windyadmin
Charter Member
8251 posts
Dec-10-08, 07:04 PM (CST)
Click to EMail windy Click to send private message to windy Click to view user profileClick to add this user to your buddy list  
4. "RE: negative HSV blood test?"
In response to message #3
 
Labcorp has their own test, which is similar to the herpeselect, but I've never seen published stats on the performance of that test compared to any others. Western Blot is about 98% sensitive for hsv2, and herpeselect is about 95% sensitive.

Different sources will give slightly different stats, but they're close, and you have to pay attention to what they're using for a comparison. Sometimes they'll compare to WB, and sometimes they'll compare to known culture positive (like I just did with the figures I gave you.) One way to improve the reliability of testing is to use different kinds of tests. Sometimes one will be positive and the other negative.

Having a pre-existing hsv1 infection can delay seroconversion for hsv2, but very few people will take longer than six months. Over the nine years I've been here, there have been around half a dozen people who took between six and twelve months to show positive on hsv2. I know that one of them had a positive, typed culture, tested negative for hsv1 and had no history of cold sores, and I'm not sure about the others.

My usual advice is to get a copy of the lab report. If the culture was really typed, it'll say so. If it doesn't, then your doctor made an assumption about which type infects which location.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
zuzzy
Member since Dec-10-08
3 posts
Dec-11-08, 03:35 PM (CST)
Click to EMail zuzzy Click to send private message to zuzzy Click to view user profileClick to add this user to your buddy list  
5. "RE: negative HSV blood test?"
In response to message #4
 
   I did get a copy of the second lab report (as I had the same fear, or even that an IGM test was used) and it was most definitely typed. The type 2 results were "<.91"

For your own info, I tested positive for type 1 but have no history of cold sores as long as I can remember.

Also:
As I understand it, seroconversion means the developing of antibodies to some particular bug. If I am in fact taking longer to seroconvert, does that mean my symptoms will decrease once I do seroconvert to measurable quantities?

Right now I'm experiencing symptoms more often than I would like so I'm hopeful that my symptoms will decrease over time (as some suggest is likely with herpes).


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
windyadmin
Charter Member
8251 posts
Dec-11-08, 04:04 PM (CST)
Click to EMail windy Click to send private message to windy Click to view user profileClick to add this user to your buddy list  
6. "RE: negative HSV blood test?"
In response to message #5
 
It is likely that your symptoms will decrease over time. The first year or two are generally worse than later. But the antibodies that the blood tests detect are not your main defense against the virus. It's your T-cells that do most of the work. We don't measure those, because it's easier to measure the circulating antibodies for diagnosis.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
auntiejessiadmin
Member since May-14-05
18073 posts
Dec-11-08, 05:51 PM (CST)
Click to send private message to auntiejessi Click to view user profileClick to add this user to your buddy list  
7. "RE: negative HSV blood test?"
In response to message #6
 
Have you considered that you have type 1 genitally?

Aj

"In those times you seem to forget, I don't mind reminding you that you are a beautiful soul." ~ Cindy Campo

Paragraphs are beautiful things.

You can google, too.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
graceadmin
Charter Member
13334 posts
Dec-12-08, 07:38 AM (CST)
Click to send private message to grace Click to view user profileClick to add this user to your buddy list  
8. "RE: negative HSV blood test?"
In response to message #7
 
If you are posting on the herpes forum on medhelp then I'm already helping you there ( or jess is on the std forum there ).

At this point if you had a + hsv2 lesion culture previously and are now having negative blood tests for hsv2 you are better off just confirming your hsv2 infection with another lesion culture and typing. If you are having ob's that often it shouldn't take long to do this. No reason for continued blood tests at this time - just go with the lesion culture if you feel the need to confirm your hsv infection.

grace

The first step in stopping the perceived stigma about genital herpes - is to stop believing in it yourself


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Angelika
Member since Aug-18-08
2252 posts
Dec-12-08, 08:12 PM (CST)
Click to send private message to Angelika Click to view user profileClick to add this user to your buddy list  
9. "RE: negative HSV blood test?"
In response to message #8
 
   to the OP, one possibility that I didn't see mentioned (but it might have been i just skimmed through the responses) is that you got a wrong blood test such as the IgM. What you need is a type specific IgG test or as Windy mentioned a Western Blot.

did you used to get outbreaks at first? is that how your partner became infected?

do you remember ever having cold sores?

Who among mortals may boast himself born with a fortune beyond reach of harm? - Aeschylus


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
auntiejessiadmin
Member since May-14-05
18073 posts
Dec-12-08, 09:23 PM (CST)
Click to send private message to auntiejessi Click to view user profileClick to add this user to your buddy list  
10. "RE: negative HSV blood test?"
In response to message #9
 
I don't see where she's had a type 2 culture?

Aj

"In those times you seem to forget, I don't mind reminding you that you are a beautiful soul." ~ Cindy Campo

Paragraphs are beautiful things.

You can google, too.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top

Conferences | Topics | Previous Topic | Next Topic

 

Advertisements appearing on this page do not constitute any endorsement of 
those products or services by HHP or its management.

All opinions expressed here by the HHP, its management and participants constitute just that, opinions.
No medical relationship with any participant is implied in any way.
Each individual's personal doctor is responsible for the medical advice and care of that person.